The opportunity cost of androgen suppression in locally advanced prostate cancer
نویسندگان
چکیده
منابع مشابه
The opportunity cost of androgen suppression in locally advanced prostate cancer.
T he use of androgen suppression therapy (AST) and radiotherapy for locally advanced prostate cancer has become the standard of care worldwide. At the same time, it has become clear that AST carries significant risk for side effects. Recently, Denham and colleagues have reported initial quality of life (QoL) results from the TROG 03.04 RADAR trial. The authors identify clinically meaningful dec...
متن کاملCost-effectiveness of androgen suppression therapies in advanced prostate cancer.
BACKGROUND The costs and side effects of several antiandrogen therapies for advanced prostate cancer differ substantially. We estimated the cost-effectiveness of antiandrogen therapies for advanced prostate cancer. METHODS We performed a cost-effectiveness analysis using a Markov model based on a formal meta-analysis and literature review. The base case was assumed to be a 65-year-old man wit...
متن کاملLocally advanced prostate cancer
The management of all stages of prostate cancer is an increasingly complex process and involves a variety of available treatments and many disciplines. Despite prostate-specific antigen (PSA) testing, the presentation of prostate cancer at a locally advanced stage is common in the UK, accounting for one-third of all new cases. There is no universally accepted definition of locally advanced pros...
متن کاملRelative effectiveness and cost-effectiveness of methods of androgen suppression in the treatment of advanced prostate cancer.
OBJECTIVES With 184,500 new cases and 39,200 deaths anticipated in 1998, prostate cancer is second only to lung cancer in cancer mortality for men. This report is a systematic review of the evidence from randomized controlled trials on the relative effectiveness of alternative strategies for androgen suppression as treatment of advanced prostate cancer. Three key issues are addressed: (1) the r...
متن کاملAB37. The combination of I brachytherapy with intermittent androgen deprivation in treating locally advanced prostate cancer
Objective: To evaluate the clinical efficacy of combination of intermittent androgen deprivation and I brachytherapy (BT) for the treatment of locally advanced prostate cancer. Method: A total of 31 patients with locally advanced prostate cance were treated with the Combination Of I Brachytherapy and Intermittent Androgen Deprivation. Bicalutamide 50 mg Qd and Goserelin 3.6 mg every 28 days wer...
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ژورنال
عنوان ژورنال: Asian Journal of Andrology
سال: 2013
ISSN: 1008-682X,1745-7262
DOI: 10.1038/aja.2012.166